MDI Biological Laboratory

Archive for: zebrafish

New Horizons for the Treatment of Diabetic Complications

Chronic complications of diabetes are the leading cause of morbidity and mortality not only in the western world but worldwide. The metabolic changes caused by diabetes, especially hyperglycemia (high blood sugar levels), can lead over time to damage in the circulation system of the diabetic patient. Subsequent ischemia (inadequate blood supply reaching organs) occurs, as...

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Women In Science Day 2021 – Olivia Aries

To mark Women in Science Day on February 11, 2021, we’re sharing the stories of female scientists, past and present, at the MDI Biological Laboratory. Olivia Aries: Making Her Own Path The global pandemic has upended all aspects of life, and millions of college students have had their education disrupted, deferred, or differ drastically from...

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From the Bench to the Bedside – A Long Affair with Diabetic Nephropathy

All my life I have been interested in studying the complications of diabetes. Diabetes has two sides: on the one hand it is a metabolic disorder that effects glucose levels, and the metabolism is treated by medications that lower glucose. On the other hand, over time diabetes leads to damaging changes in the vascular bed,...

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How chronic stress undermines the immune system: a new piece in the puzzle

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Alumni Spotlight: Katharine Bancroft

Katharine Bancroft is a physics major at Haverford College. While she has always had an interest in biology, her true passion is studying soft matter as with a focus on applications. Her long term goal is to pursue a Ph.D. in physics and innovative work in a field such as prosthetic design or battery development....

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Restoring the Ability to Repair and Regenerate As We Age

“If everything regenerated, there would be no death.” Richard J. Goss, Ph.D.Principles of Regeneration Richard J. Goss, Ph.D., author of Principles of Regeneration, was a visiting scientist at the MDI Biological Laboratory in the late 1960’s and early 1970’s. But is the statement that there would be no death if everything regenerated correct? The zebrafish,...

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Course Spotlight >> The Colby INBRE Course: Taking the Cookie Cutter Out of STEM Education

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Research Models Less Traveled By

The following interview with Kevin Strange, Ph.D., president of the MDI Biological Laboratory, is excerpted from Eureka, a blog serving the CRO (contract research organization) industry. Launched by Charles River Labs in 2012, the site is a way for scientists to connect and share big ideas on the cutting-edge bench science driving drug discovery and development, particularly in the areas of preclinical safety and assessment, pharmaceutical manufacturing and animal research models.

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What If Stimulating Regeneration Were As Simple As Taking a Drug?

This excerpt from the MDI Biological Laboratory's biannual news magazine, "Breaking Through," describes the institution's pioneering approach to regenerative medicine.

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