MDI Biological Laboratory

Archive for: regeneration

Comparative Biology: Animal Models Strut Their Stuff

  At MDIBL, researchers are particularly focused on the mechanisms of aging and regeneration. Non-mammalian model organisms like C. elegans, zebrafish, African turquoise killifish, and the axolotl regenerate naturally in ways that humans cannot. By decoding the instruction manual for their regenerative abilities, we can develop new strategies to enhance our natural ability to repair…

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Visiting Scientist Brett Keiper, Ph.D.: Taking the Time for Creative Inspiration

Everyone is familiar with bursts of creative inspiration in which ideas are teeming, connections between disparate subjects are made and solutions to seemingly intractable problems are revealed. But it’s rare for such moments to come out of the blue. Often, they are fostered by an inspirational setting, a culture of knowledge-sharing and the time to…

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Who Is Coming to the Regeneration Party?

MDI Biological Laboratory scientist, James Godwin, Ph.D., who studies heart and limb regeneration in the axolotl, a highly regenerative Mexican salamander, likes to compare the process of regeneration that takes place at the site of an injury to a party. Over the course of his career, he has identified who comes to the regeneration party…

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Meet Our Postdocs: Emily Spaulding, Ph.D.

Dr. Emily Spaulding graduated from the University of Maine Graduate School of Biomedical Science and Engineering in 2019. She joined the MDI Biological Laboratory as a postdoctoral fellow in the Updike Lab, just two months before the COVID-19 pandemic restrictions began. While her first year at MDI Biological Laboratory was challenging, she highlighted two areas…

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Meet Our Postdocs: Marko Pende, Ph.D.

When Prayag Murawala, Ph.D., was recruited as a new faculty member to MDI Biological Laboratory in 2020, it only took a few months for colleague Marko Pende, Ph.D., to follow him to Maine as a postdoctoral researcher. Marko and Prayag collaborated on a paper while they were both completing different stages of their education and…

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Another Successful Summer at MDIBL

Walking through the MDI Biological Laboratory courtyard on a sultry August afternoon, you couldn’t help but be inspired by the depth and breadth of research from our 2021 student fellows. 45 undergraduate and high school students from institutions across the country, working with mentors at MDIBL and other INBRE institutions around Maine, spent 10 weeks…

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Making a Mouse More Like an Axolotl: How James Godwin’s Discoveries Are Helping Science ‘Pull the Levers of Regeneration’

Science is now inching closer to the answer thanks to new research by MDI Biological Laboratory scientist James Godwin, Ph.D. Following in the laboratory’s tradition of using comparative biology to gain insights into human health, Godwin has compared the molecular mechanisms governing regeneration in a highly regenerative salamander to those in the mouse, which has…

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Research by Iain Drummond, Ph.D., Brings Science Closer to Kidney Replacement Tissue

Each of the body’s approximately one million nephrons, the functional units of the kidney, contains a glomerulus, or a cluster of blood vessels where filtration takes place. The membranes of the glomeruli are lined with specialized cells called podocytes, which have tiny, foot-like projections (podo means “having a foot” in Latin) that protrude into the…

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Women In Science Day 2021 – Margaret Reed Lewis

To mark Women in Science Day on February 11, 2021, we’re sharing the stories of female scientists, past and present, at the MDI Biological Laboratory. Margaret Reed Lewis, Ph.D.: A Pioneer in Tissue Culture In 1908, Margaret Reed was working in a laboratory in Germany when she explanted a small piece of tissue from a…

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