MDI Biological Laboratory

Archive for: Organ Regeneration

Research by Iain Drummond, Ph.D., Brings Science Closer to Kidney Replacement Tissue

Each of the body’s approximately one million nephrons, the functional units of the kidney, contains a glomerulus, or a cluster of blood vessels where filtration takes place. The membranes of the glomeruli are lined with specialized cells called podocytes, which have tiny, foot-like projections (podo means “having a foot” in Latin) that protrude into the…

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Attracting Students from Around the Globe

Course offers extensive laboratory training The MDI Biological Laboratory’s Applications of Organoid Technology course, held in May for the second consecutive year, is the only course in the world offering extensive laboratory training in making organoids. “Our course is called ‘Applications of Organoid Technology’ for a reason,” said course director Hugo de Jonge, Ph.D., a…

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Report from the 2016 American Society of Nephrology Kidney Week: Using Stem Cells and Organoids to Build a New Kidney

Nephrologists have always been interested in basic biology. At the MDI Biological Laboratory, scientists have been making major scientific contributions to the understanding of the molecular mechanisms of renal tubules and their implications for salt and water balance — and hence their effect on disease — for nearly a century. In recent years, the focus…

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What If Stimulating Regeneration Were As Simple As Taking a Drug?

This excerpt from the MDI Biological Laboratory’s biannual news magazine, “Breaking Through,” describes the institution’s pioneering approach to regenerative medicine.

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Looking Beyond Stem Cells and Tissue Engineering: What if Lost and Damaged Tissues and Organs Could Be Regenerated Simply by Taking a Drug?

MDI Biological President Kevin S. Strange, Ph.D., discusses the laboratory’s pioneering approach to regenerative medicine in an editorial that originally appeared in the online publication, Regenerative Medicine Network.

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Dream of Regenerating Human Body Parts Gets a Little Closer

Science is getting closer to achieving the dream of being able to restore damage to vital organs, the spinal cord and limbs. MDI Biological Laboratory scientist James Godwin, Ph.D., discusses this progress in an article originally published in “The Conversation,” a news outlet for the academic and research community based in Australia, where Godwin was formerly a research fellow at the Australian Regenerative Medicine Institute (ARMI).

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MDI Biological Laboratory Scientists Awarded Patent for Potential New Heart Disease Drug

The U.S. Patent and Trademark Office has announced that it will grant a patent to MDI Biological Laboratory scientists Voot P. Yin, Ph.D., and Kevin Strange, Ph.D., and their collaborator Michael Zasloff, M.D., Ph.D., for use of the small molecule MSI-1436 to stimulate the repair and regeneration of heart tissue.

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Limb and Organ Regeneration Featured on “Maine Calling,” MPBN’s Popular Radio Call-In Program

Though it sounds like science fiction, limb regeneration in humans is within the realm of possibility. The study of limb regeneration can also lead to advances in wound healing and in the development of highly sophisticated prosthetic devices that are much more sensitive and effective than those that are currently in use. MDI Biological Laboratory…

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