MDI Biological Laboratory

Archive for: C.elegans

Microscopy in Focus for Maine INBRE Students

Students and young science faculty from all around Maine converged on MDI Bio Lab’s campus for an intensive 10-day course on the use of the most modern microscopy of the day.

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2022 MDI Biological Laboratory Publications

In 2022 MDI Biological Laboratory’s researchers continued to push into new scientific frontiers in the biology of aging, repair and regeneration, expanding our knowledge of how to protect and extend healthy lifespans. 

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HoL1day Tree

Hannah Somers, a research assistant in the Rollins lab, created this composite image of L1 C. elegans. C. elegans have four larval stages before adulthood – L1 is the first larval stage after hatching. These images were taken to understand how intermittent fasting impacts L1 C. elegans and protein translation rates. L1 C. elegans enter an ageless state of arrest when fasted, making...

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Tiny Worlds, Big Science: MDIBL Scientists See Deeper Inside the Cell

Sometimes a new tool can spur a scientist to unexpected discoveries. 

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Will CRISPR/Cas9 be the Catalyst that Revolutionizes Human Health?

At the MDI Biological Laboratory (MDIBL), the importance of answering that question has put scientists on the front lines of research. 

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Comparative Biology: Animal Models Strut Their Stuff

Scientists at the MDI Biological Laboratory use the comparative model approach to understand the basic biology of tissue regeneration and aging. Thanks to evolution and common ancestry, we humans actually share a large portion of our DNA with fish, worms, and salamanders. Humans and zebrafish, for example, share 70% of the same genes; 84% of human genes known to be associated with human disease have a zebrafish equivalent. That’s a lot of similarity. 

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New Research by Aric Rogers, Ph.D., Sheds Light on the Effects of Dietary Restriction on Muscle Tissue

Consider the following scenarios: In the first, a thin young woman who exercises excessively develops athletic amenorrhea, or stops menstruating, rendering her incapable of bearing children. In the second, a sedentary, overweight girl undergoes menarche at a precociously early age. Aric N. Rogers, Ph.D., who studies aging at the MDI Biological Laboratory, believes these scenarios...

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Visiting Scientist Brett Keiper, Ph.D.: Taking the Time for Creative Inspiration

This is the second in a series of posts describing how collaborations between MDI Biological Laboratory faculty members and visiting scientists are advancing scientific progress.

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Meet Our Postdocs: Dilawar Mir, Ph.D.

Dilawar Mir, Ph.D., is a postdoctoral researcher in the Rogers Lab, working the animal model C. elegans. He focuses on dietary restriction and extending lifespan in the short-lived worm.

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