2022 MDI Biological Laboratory Publications
In 2022 MDI Biological Laboratory’s researchers continued to push into new scientific frontiers in the biology of aging, repair and regeneration, expanding our knowledge of how to protect and extend healthy lifespans.
Continue ReadingHoL1day Tree
Hannah Somers, a research assistant in the Rollins lab, created this composite image of L1 C. elegans. C. elegans have four larval stages before adulthood – L1 is the first larval stage after hatching. These images were taken to understand how intermittent fasting impacts L1 C. elegans and protein translation rates. L1 C. elegans enter an ageless state of arrest when fasted, making...
Continue ReadingTiny Worlds, Big Science: MDIBL Scientists See Deeper Inside the Cell
Sometimes a new tool can spur a scientist to unexpected discoveries.
Continue ReadingWill CRISPR/Cas9 be the Catalyst that Revolutionizes Human Health?
At the MDI Biological Laboratory (MDIBL), the importance of answering that question has put scientists on the front lines of research.
Continue ReadingComparative Biology: Animal Models Strut Their Stuff
Scientists at the MDI Biological Laboratory use the comparative model approach to understand the basic biology of tissue regeneration and aging. Thanks to evolution and common ancestry, we humans actually share a large portion of our DNA with fish, worms, and salamanders. Humans and zebrafish, for example, share 70% of the same genes; 84% of human genes known to be associated with human disease have a zebrafish equivalent. That’s a lot of similarity.
Continue ReadingNew Research by Aric Rogers, Ph.D., Sheds Light on the Effects of Dietary Restriction on Muscle Tissue
Consider the following scenarios: In the first, a thin young woman who exercises excessively develops athletic amenorrhea, or stops menstruating, rendering her incapable of bearing children. In the second, a sedentary, overweight girl undergoes menarche at a precociously early age. Aric N. Rogers, Ph.D., who studies aging at the MDI Biological Laboratory, believes these scenarios...
Continue ReadingVisiting Scientist Brett Keiper, Ph.D.: Taking the Time for Creative Inspiration
This is the second in a series of posts describing how collaborations between MDI Biological Laboratory faculty members and visiting scientists are advancing scientific progress.
Continue ReadingMeet Our Postdocs: Dilawar Mir, Ph.D.
Dilawar Mir, Ph.D., is a postdoctoral researcher in the Rogers Lab, working the animal model C. elegans. He focuses on dietary restriction and extending lifespan in the short-lived worm.
Continue ReadingMeet Our Postdocs: Zhengxin Ma, Ph.D.
Zhengxin Ma, Ph.D., is a postdoctoral researcher in the Rogers Lab. She uses C. elegans to study how dietary restriction can increase lifespan and protect against age-related diseases.
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