MDI Biological Laboratory

Archive for: C.elegans

Tiny Worlds, Big Science: MDIBL Scientists See Deeper Inside the Cell

MDI Biological Laboratory’s Emily Spaulding, Ph. D., is using advanced “super-resolution” microscopy to peer deep within the active cells of a tiny, transparent roundworm called C. elegans. What she’s found there is a powerful new tool for studying the functions of a common gene protein called Nucleolin. And the work offers a challenge to some…

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Will CRISPR/Cas9 be the Catalyst that Revolutionizes Human Health?

Associate professor, Dustin Updike, Ph.D., is internationally recognized for using CRISPR/Cas9 in his research. CRISPR/Cas9 is a gene-editing technology revolutionizing scientific research and experimental therapies in human health. A genome, the term used to describe all of an organism’s DNA as a whole, is like a blueprint laying out the directions for an organism’s body…

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Comparative Biology: Animal Models Strut Their Stuff

  At MDIBL, researchers are particularly focused on the mechanisms of aging and regeneration. Non-mammalian model organisms like C. elegans, zebrafish, African turquoise killifish, and the axolotl regenerate naturally in ways that humans cannot. By decoding the instruction manual for their regenerative abilities, we can develop new strategies to enhance our natural ability to repair…

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New Research by Aric Rogers, Ph.D., Sheds Light on the Effects of Dietary Restriction on Muscle Tissue

Consider the following scenarios: In the first, a thin young woman who exercises excessively develops athletic amenorrhea, or stops menstruating, rendering her incapable of bearing children. In the second, a sedentary, overweight girl undergoes menarche at a precociously early age. Aric N. Rogers, Ph.D., who studies aging at the MDI Biological Laboratory, believes these scenarios…

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Visiting Scientist Brett Keiper, Ph.D.: Taking the Time for Creative Inspiration

Everyone is familiar with bursts of creative inspiration in which ideas are teeming, connections between disparate subjects are made and solutions to seemingly intractable problems are revealed. But it’s rare for such moments to come out of the blue. Often, they are fostered by an inspirational setting, a culture of knowledge-sharing and the time to…

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Meet Our Postdocs: Dilawar Mir, Ph.D.

The pull of C. elegans drew Dilawar Mir, Ph.D. to the Rogers Lab at the MDI Biological Laboratory for his postdoctoral research. Born and raised in the Kashmir Valley, Mir earned his Ph.D. from Alagappa University in India in 2019. His graduate research focused on understanding host-pathogen interactions in the context of the whole organism;…

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Meet Our Postdocs: Zhengxin Ma, Ph.D.

Zhengxin first encountered C. elegans during her graduate studies at the University of Florida, where she earned a M.S. in animal nutrition and a Ph.D. in animal microbiology, studying how to mitigate antimicrobial-resistant pathogens. She used the model to test the toxicity of bacterial toxins and chemicals and was hooked. When it came time to…

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Meet Our Postdocs: Hyemin Min, Ph.D.

Hyemin is one of the newest postdoctoral researchers to join the MDI Biological Laboratory, arriving in July 2021 to begin her final stage of scientific training. She hails from Seoul, Korea and completed her master’s and doctoral degrees at Konkuk University of Korea. Under the guidance of her advisor, Professor Yhong-Hee Shim, she studied the…

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Will You Invest in The Future of Science?

We’re pleased to introduce you to Hyemin Min, Ph.D., a postdoctoral researcher who joined the MDI Biological Laboratory in July. Working alongside Dr. Dustin Updike, Hyemin studies the development of the reproductive system in C. elegans (a short lived, microscopic worm). Her work is shedding light on the causes of infertility. Hyemin will spend three to five…

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