MDI Biological Laboratory

Scientists at the MDI Biological Laboratory Are Unlocking the Mechanisms of Parkinson’s Disease

  • May 6, 2016

Scientists at the MDI Biological Laboratory are identifying the basic mechanisms behind Parkinson’s disease, a degenerative neurological disease affecting millions of people worldwide. The research could some day lead to treatments for a disabling condition for which medicine now has nothing to offer other than symptomatic relief.

Parkinson’s is a progressive disorder of the nervous system that causes tremors, stiffness, slowed movement and impaired balance and coordination. The disease affects nearly 1 million people in the United States alone and is age-related: the average age of onset is 60 and the incidence rises sharply with age.

Assistant professor Aric Rogers, Ph.D., is investigating ways of enhancing basic mechanisms to keep cells healthy and resistant to conditions that can lead to Parkinson’s. By lowering the activity of a specific gene, his team was able to reduce the toxicity of malformed proteins associated with Parkinson’s and increase cell health.

Read more about the work of Rogers and his team on Parkinson’s…

More From The Blog

UNE, MDIBL Team up for Drinking Water Initiative

Collaboration with “Legacy Scholars” builds on the Laboratory’s “All About Arsenic” citizen science initiative

Continue Reading

HoL1day Tree

Hannah Somers, a research assistant in the Rollins lab, created this composite image of L1 C. elegans. C. elegans have four larval stages before adulthood – L1 is the first larval stage after hatching. These images were taken to understand how intermittent fasting impacts L1 C. elegans and protein translation rates. L1 C. elegans enter an ageless state of arrest when fasted, making...

Continue Reading