MDI Biological Laboratory

COBRE I and COBRE II Success

The NIH Centers of Biomedical Research Excellence (COBRE) grants support institutions in IDeA-eligible states to establish and develop state-of-the-art biomedical and behavioral research centers. COBRE grants have three sequential five-year phases with a competitive application process between phases.

Previous COBRE Project Leaders

Sam Beck
Disruption of CpG Island-Mediated Gene Regulation and Chromatin Architecture in Progeria and Aging

James Coffman
Stress, genomic instability, and loss of regenerative capacity with age

James Godwin
Defining macrophage-nerve dependent signals in the regulation of limb regeneration

Vicki Losick
The molecular mechanisms regulating wound-induced polyploidy

Prayag Murawala
Understanding the role of thyroid hormone signaling during axolotl limb regeneration

Sandra Reiger
Regulation of Cutaneous Axon Regeneration by Wound-derived H2O2

Jarod Rollins
Defining the roll of Ribosome protein composition on regulating the selective translation of pro-longevity genes

Dustin Updike
The Role of Germ Granules in Maintaining Cellular Self-renewal and Totipotency

Voot Yin
Genetic Analysis of Natural Reprogramming during Regeneration