Scientists have known for decades that drastically restricting certain nutrients without causing malnutrition prolongs health and lifespan in a wide range of species, but the molecular mechanisms underlying this effect have remained a mystery. In a paper recently published in the journal Aging Cell, MDI Biological Laboratory scientist Aric Rogers, Ph.D., sheds light on an important genetic pathway underlying this process, raising the possibility that therapies can be developed that can…
Scientists have long known that chronic exposure to psychosocial stress early in life can lead to an increased vulnerability later in life to diseases linked to immune dysfunction and chronic inflammation. Developmental biologist James A. Coffman, Ph.D., of the MDI Biological Laboratory in Bar Harbor, Maine, and his team are beginning to elucidate the mechanisms underlying this phenomenon.
The MDI Biological Laboratory will offer three lectures for the public on the science of aging as part of its new signature course on aging. The presenters, all leaders in the field of aging research, will address tantalizing questions such as why do we age, what mechanisms regulate aging on a cellular level and can youthfulness be extended through genetic manipulation?
MDI Biological Laboratory Associate Professor James A. Coffman, Ph.D., is studying the regenerative capacity of sea urchins in hopes that a deeper understanding of the process of regeneration, which governs the regeneration of aging tissues as well as lost or damaged body parts, will lead to a deeper understanding of the aging process in humans, with whom sea urchins share a close genetic relationship.
Why do we age? What are the mechanisms that regulate aging on a cellular level? Is it possible to extend youthfulness through genetic manipulation? These are some of the tantalizing questions that will be the subject of a new signature course at the MDI Biological Laboratory, in Bar Harbor, Maine, that will address fundamental issues related to aging.
MDI Biological Laboratory scientist Vicki P. Losick, Ph.D., has identified a new mechanism for wound healing that has wide-ranging therapeutic potential for the treatment of injury, disease and even aging.
Scientists at the MDI Biological Laboratory are identifying the basic mechanisms behind Parkinson’s disease, a degenerative neurological disease affecting millions of people worldwide. The research could some day lead to treatments for a disabling condition for which medicine now has nothing to offer other than symptomatic relief.
The MDI Biological Laboratory has announced that it has received a grant to support a new course on aging that will draw internationally renowned scientists to Bar Harbor, Maine, to examine fundamental questions about our ability to repair and regenerate tissue as we age.
The role of dietary restriction in extending lifespan is the subject of research being conducted at the MDI Biological Laboratory in Bar Harbor, Maine, by visiting scientist Markus Schosserer, Ph.D., of the biotechnology department at the University of Natural Resources and Life Sciences, Vienna, in Austria.
New MDI Biological Laboratory faculty member Vicki Losick, Ph.D., is leading a research team focused on understanding how damaged cells repair themselves and how the ability to heal declines as we age.