We’re all familiar with the short-term stress caused by election politics or our favorite sports team, but researchers at the MDI Biological Laboratory are looking at how chronic exposure to stress early in life may lead adults to be more vulnerable to costly diseases linked to chronic inflammation like arthritis, cancer and diabetes.
Peripheral neuropathy is usually associated with diabetes, but it’s also a common side effect of some chemotherapy drugs. Sandra Rieger, Ph.D., a scientist at the MDI Biological Laboratory in Bar Harbor, recently discovered where and how neuropathy begins when someone is on chemotherapy. It’s an important finding because ultimately it should lead to some effective treatments.
In this interview, Vicki P Losick, PhD, of the MDI Biological Laboratory (Bar Harbor, ME, USA), discusses her research into the pathways involved in wound healing and the considerations involved in translating this knowledge into clinical outcomes.
If you enjoy action movies, you can probably think of a superhero—maybe Wolverine?—who can lose a limb in battle, yet grow it right back and keep on going. But could regenerating a lost limb ever happen in real life? Some scientists are working hard to understand how other organisms do this.
What turns a student into a scientist? It’s a combination of inquiry, mentoring, curiosity and a chance to actually try it all out for real. That’s what two educational institutions, Colby College and the Mount Desert Island Biological Laboratory, are providing high school students through programs designed to give students a chance to take an early look at science in depth.
The top of the food chain can learn quite a bit from those at the bottom. While some fish and other lower organisms can regenerate tissue, we humans lag behind. Scientists at the MDI Biological Laboratory in Bar Harbor, Maine, are digging into the genes of these enviable organisms to learn how to activate such regenerative mechanisms in humans. They have just identified genetic regulators governing regeneration that are common across species.
At the MDI Biological Laboratory, scientists study lower organisms that have retained the miraculous ability to regenerate organs and tissues. Dr. Voot Yin talks about how research on the common aquarium fish, the zebrafish, may lead to a drug to regenerate healthy heart tissue after a heart attack.
If the axolotl loses a limb after injury, the salamander is able to regrow it. Someday, researchers hope, humans will be able to do this as well.
What’s in your drinking water? Arsenic has a greater impact on human health than any other environmental contaminant.
Recent research by Sandra Rieger, Ph.D., of the MDI Biological Laboratory identifying the underlying mechanisms of peripheral neuropathy, or nerve damage, has raised the prospect that drug therapies can be developed for the treatment of this condition, which causes pain, numbness and/or tingling in the hands and feet.