In an era of big data, many biological problems can be resolved through computational analysis and bioinformatics. These disciplines analyze large biological datasets using computer science, statistics and mathematical modeling to understand biological systems and relationships. Research in my laboratory is focused on adapting computational analysis and bioinformatics to biological problems while also relying on traditional experiments to validate bioinformatics-based predictions. We are employing big data analytics, genomics and cell biology to understand the comprehensive biological mechanisms underlying gene regulation in human aging, and how dysregulation of gene expression is associated with reduced lifespan and age-related disease. In particular, my laboratory is focused on the study of progeria, or Hutchinson-Gilford progeria syndrome, a rare, fatal genetic condition characterized by accelerated aging in children. The name, which is derived from the Greek, means “prematurely old.” The aim of my research is to gain new insight into the molecular mechanisms underlying aging with the ultimate goal of developing therapeutics to extend healthy human lifespan and slow the onset of age-related degenerative diseases.
Scientist Focuses on Accelerated Aging in Children
Mount Desert Islander · December 9, 2017
Sam Beck, Ph.D., Joins MDI Biological Laboratory Faculty in Computational Biology
Press Release · September 7, 2017