MDI Biological Laboratory
Senior Staff Scientist, Director of Computational Biology and Bioinformatics Core

Joel H. Graber, Ph.D.

Modern biomedical research is increasingly data-intensive and requires computational expertise and robust procedures that ensure rigorous and reproductive analysis.

The MDI Biological Laboratory Computational Biology/Bionformatics (CompBio) Core is focused on collaboration, analysis, and education in the computational analysis of genome-scale data. Their efforts are distributed between the linked goals of (1) providing our collaborating research groups with experimental data analysis/management and computational resources, and (2) providing training in computational biology both within MDIBL and also as part of the Maine INBRE (IDeA Networks of Biomedical Research Excellence) research program.

Biomedical research is dependent on data management and increasingly sophisticated analysis workflows that are both rigorous and reproducible. The CompBio Core has the experience and knowledge to provide training, analysis, and infrastructure that enable our collaborating researchers to accomplish their research goals.

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Education

  • Ph.D., Cornell University, Experimental Accelerator Physics, 1993
  • B.S., Michigan Technological University, Physics, 1987
  • B.S., Michigan Technological University, Computer Science, 1987

Student Projects

Research Fellow projects working within the CompBio Core are focused on analysis and interpretation of genome-scale data.

Projects that address biological problems of interest are generally carried out in collaboration with wet-bench researchers from MDIBL as well as visiting or INBRE-partner research groups. Core personnel also support computationally-focused projects that emphasize “best practices” in developing rigorous and reproducible tools, workflows, and databases. Summer projects are discrete, targeted towards analysis or tool development, and can be carried out over the course of 10 weeks. The CompBio Core is also open to academic year internships focused on longer-term projects.

Lab Members

Nathaniel MakiBioinformatics Training Specialist and Analyst

Christian WilsonBioinformatics Software Engineer