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Finding regenerative strategies capable of faithfully repairing tissues after surgery, disease or traumatic injury will have the potential to transform modern medicine and improve the lives of a limitless number of patients.
In dramatic contrast to the poor repair outcomes for humans and rodent models such as mice, salamanders are able to completely regenerate heart tissue, whole limbs and many other tissues following injury, at any life stage. This astounding capacity for repair provides a template on which to understand the process of natural regeneration and develop strategies to improve human repair.
Dr. Godwin’s work explores the molecular signals from nerve and immune cells that underpin the resistance to scarring, and the activation of regeneration in salamanders. This work combines both comparative biology and immunomodulation to investigate the potential for regeneration in a range of genetic mouse models.
Dr. Godwin holds a dual appointment at the MDI Biological Laboratory and the Jackson Laboratory.
MDI Biological Laboratory Study Finds Immune System Is Critical to Regeneration
Press Release · September 20, 2017
MDI Biological Laboratory Celebrates Banner Year
Mount Desert Islander · August 2, 2017
MDI Biological Laboratory to Offer Signature Course in Comparative Regenerative Biology
Press Release · March 15, 2017
Introduction to the MDI Biological Laboratory’s Center for Science Entrepreneurship
Regenerative Medicine Network · March 7, 2017
James Godwin, Ph.D. Joins Faculty at the MDI Biological Laboratory
Bangor Daily News · December 22, 2016
James Godwin, Ph.D., Joins Faculty at the MDI Biological Laboratory
Press Release · December 19, 2016
Dream of Regenerating Human Body Parts Gets a Little Closer
Breaking Through · November 28, 2016