- Regeneration of human limbs and organs – science fact or science fiction? Metastellar · February 28, 2022
- Who Is Coming to the Regeneration Party? Blog · November 17, 2021
- Making a Mouse More Like an Axolotl: How James Godwin’s Discoveries Are Helping Science ‘Pull the Levers of Regeneration’ Blog · November 17, 2021
- Debuque RJ, Nowoshilow S, Chan KE, Rosenthal NA, Godwin JW. Distinct toll-like receptor signaling in the salamander response to tissue damage. Dev Dyn. 2022 Jun;251(6):988-1003. doi: 10.1002/dvdy.340. Epub 2021 Apr 8. PMID: 33797128; PMCID: PMC8484370.
- Dastagir N, Beal Z, Godwin J. Tissue origin of cytotoxic natural killer cells dictates their differential roles in mouse digit tip regeneration and progenitor cell survival. Stem Cell Reports. 2022 Jan 24:S2213-6711(22)00050-9. doi: 10.1016/j.stemcr.2022.01.006. Epub ahead of print. PMID: 35120621.
- Lee JY, Davis I, Youth EHH, Kim J, Churchill G, Godwin J, Korstanje R, Beck S. Misexpression of genes lacking CpG islands drives degenerative changes during aging. Sci Adv. 2021 Dec 17;7(51):eabj9111. doi: 10.1126/sciadv.abj9111. Epub 2021 Dec 15. PMID: 34910517.
- Debuque RJ, Hart AJ, Johnson GH, Rosenthal NA, Godwin JW. Identification of the adult hematopoietic liver as the primary reservoir for the recruitment of pro-regenerative macrophages required for salamander limb regeneration. Front Cell Dev Biol. 2021 Sep 22;9:750587. doi: 10.3389/fcell.2021.750587. PMID: 34568347; PMCID: PMC8456783.
Postdoctoral Fellow, Australian Regenerative Medicine Institute, ARMI, Monash University, Australia
Postdoctoral Fellow, University College London, UCL (UK)
Ph.D., Immunology Research Center, Melbourne University, Australia.
Dr. Godwin studies the requirements for successful limb and heart regeneration in salamanders. He has shown that salamander macrophages are a cell type essential for regeneration and that the behavior of connective tissue cells (fibroblasts) behave differently in the absence of macrophages. Undergraduate Research Fellows in Dr. Godwin’s lab will develop new transgenic animals and characterize nerve-fibroblast-macrophage interactions using in vivo assays and targeted cell ablation to define critical cell types and subtypes and in vivo imaging to record critical interactions.