Aric Rogers, Ph.D.

Our lab uses the small roundworm C. elegans to study how gene expression is remodeled under conditions that extend lifespan, particularly at points of regulation that occur after transcription. Genetic variations and environmental conditions that result in lifespan extension are also associated with delaying the onset of age-related diseases including diabetes, cancer, and neurodegeneration. The goal of our lab is to understand how life-extending interventions work across different species and apply what is learned to extend human health and longevity.

Student Spotlight: Ratna Sharma
Breaking Through · September 18, 2020

Fishing for regenerative therapies
Longevity Technology · February 25, 2020

Cellular & Anti-aging Biology
Biotechnology Kiosk · February 18, 2020

MDI Biolab Grant Adds to Model Animal Roster
Mount Desert Islander · February 6, 2020

Synergistic Cellular Pathways Identified That Extend Lifespan by 500%
SciTechDaily · February 5, 2020

Scientists Find Mechanism That Extends Worm Lifespans by 500 Percent
Microsoft News · January 26, 2020

Advances in Quest for Immortality
The Guardian · January 23, 2020

Pathways That Extend Lifespan by 500 Percent Identified
Free Republic · January 21, 2020

Biological Pathways Which Boost Lifespan Identified
Digital Journal · January 17, 2020

MDI Biological Laboratory Will Use African Turquoise Killifish Model to Study Aging
BioPortfolio · January 16, 2020

MDI Biological Laboratory Will Use African Turquoise Killifish Model to Study Aging
News Medical: Life Sciences · January 16, 2020

MDI Biological Laboratory Will Use New Animal Model to Study Aging
Bio-IT World · January 15, 2020

MDI Biological Laboratory Will Use New Animal Model to Study Aging
Bioengineer.org · January 15, 2020

MDI Biological Laboratory Will Use New Animal Model To Study Aging
Scienmag Science Magazine · January 15, 2020

Researchers Identify Cellular Pathways that Extend Lifespan by 500%
Technology.org · January 14, 2020

Want to Live 400 Years? These Simple Nematode Worms Might Show Humans How
SyFyWire · January 14, 2020

Biologists Extend Worm Lifespan by 500% in Surprising Discovery on Aging
Big Think · January 13, 2020

MDI Biological Laboratory Will Use New Animal Model to Study Aging
Press Release · January 13, 2020

MDI Biological Scientists Identify Pathways That Extend Lifespan by 500 Percent
TerraDaily · January 13, 2020

Scientists Find Mechanism That Extends Worm Lifespans by 500 Percent – ScienceAlert
Trending News Blog · January 12, 2020

Sunday Snippets: Scientists Discover Cellular Pathways They Say Could Extend Human Life to 500 Years
Daily Kos · January 12, 2020

Scientists Find Mechanism That Extends Worm Lifespans by 500 Percent
Release Soon · January 11, 2020

Path-breaking Discovery to Slow Down Ageing Process in Future
Big News Network.com · January 11, 2020

Scientists Extend Animal's Lifespan by 500 Percent
Click Lancashire · January 11, 2020

Breakthrough Pathways Can Extend Lifespan by 500%
Tech Explorist · January 11, 2020

Extending Lifespan by 500 Percent
Fars News Agency (Iran) · January 11, 2020

Using Worms, Bar Harbor Scientists Make Discovery That Could Extend Human Life to 500 Years
Bangor Daily News · January 10, 2020

Maine Researchers Made Tiny Worms Live Longer, Discovery Could Help Humans Live 500 Years
WPFO Fox 23 Maine · January 10, 2020

Scientists Find Mechanism That Extends Worm Lifespans by 500 Percent
Science Alert · January 10, 2020

Path-breaking Discovery to Slow Down Ageing Process in Future
Asian News International · January 10, 2020

Path-breaking Discovery to Slow Down Ageing Process in Future
Business Standard · January 10, 2020

Biologists Identify Pathways That Extend Lifespan by 500%
phys.org · January 9, 2020

Scientists Have Extended the Lifespan of These Animals by 500 Percent
Head Topics · January 9, 2020

Scientists Expand The Lifespan Of A Worm By 500 Percent – The Equivalent Of 400 Years In Humans
IFL Science · January 9, 2020

Pathways That Extend Lifespan by 500% Identified
MedicallyPrime.com · January 9, 2020

Pathways That Extend Lifespan by 500% Identified
Health Medicine Network · January 9, 2020

Researchers Identify Synergistic Cellular Pathways That Considerably Amplify Lifespan
News Medical: Life Sciences · January 9, 2020

Scientists Extend Lifespan of Worms by 500 Percent
Futurism.com · January 9, 2020

Pathways That Extend Lifespan by 500% Identified: Study
Medindia · January 9, 2020

Pathways Identified in Worms That Extend Lifespan by 500%
Technology Networks · January 9, 2020

MDI Biological Scientists Identify Pathways That Extend Lifespan by 500%
7thSpace · January 9, 2020

Biologists Identify Pathways That Extend Lifespan by 500%
phys.org · January 9, 2020

Scientists Have Extended the Lifespan of These Animals by 500 Percent
Newsweek · January 9, 2020

Pathways That Extend Lifespan by 500% Identified
LongRoom News · January 8, 2020

Worm Lifespans Extended 500 Percent in Surprising New Aging Study
New Atlas · January 8, 2020

MDI Biological Scientists Identify Pathways That Extend Lifespan by 500 Percent
Press Release · January 8, 2020

Newsworthy People and Performances for Nov. 11, 2019
Mainebiz · November 17, 2019

The New Age Fountain of Youth
Grant News · November 8, 2019

Grant Supports Aging Research
Mount Desert Islander · October 26, 2019

Eating Less Can Prolong Life; Drugs Could Mimic Effect
Mount Desert Islander · October 25, 2019

Genetische Mechanismen des Alterns Aufgeklärt
Pharmazeutische Zeitung · October 17, 2019

Scientists at the MDI Biological Laboratory Are Decoding the Genetic Mechanisms of Aging and the Role of Dietary Restriction
Regen Health Solutions · October 16, 2019

Scientists are Trying to Find Ways to Slow Down the Process of Aging
Tribune Byte · October 12, 2019

Des Chercheurs Décodent le Mécanisme du Vieillissement
Pourquoi Docteur · October 12, 2019

Genetic Mechanisms Could Serve As a Road Map for Screening New Drugs to Prolong Healthy Lifespan
Ciencias Medicas News · October 12, 2019

Is Any Drug Possible in Future to Prolong Healthy Lifespan?
Discourse on Development · October 11, 2019

Decoding the Genetic Mechanisms of Aging
Technology Networks · October 11, 2019

Scientists Are Decoding the Genetic Mechanisms of Aging
Health Medicine Network · October 11, 2019

Scientists Are Decoding the Genetic Mechanisms of Aging
Science Daily · October 10, 2019

The MDI Biological Laboratory Scientist Has Been Awarded a Federal Grant for Research on Aging
ArchyNewsy.com · October 10, 2019

Scientists Are Decoding the Genetic Mechanisms of Aging
Phys.org · October 10, 2019

Genetic Mechanisms Could Serve As a Road Map for Screening New Drugs to Prolong Healthy Lifespan
News Medical: Life Sciences · October 10, 2019

MDI Biological Laboratory Scientist Awarded Federal Grant for Aging Research
News Medical: Life Sciences · October 10, 2019

Scientists at the MDI Biological Laboratory Are Decoding the Genetic Mechanisms of Aging
Bio-IT World · October 10, 2019

MDI Biological Laboratory Scientist Receives Federal Scholarship for Aging Research
Newsbreezer (Singapore) · October 10, 2019

MDI Biological Laboratory Scientist Receives Federal Grant to Study Aging
Bioengineer.org · October 10, 2019

MDI Biological Laboratory Scientist Receives Federal Grant to Study Aging
7thSpace · October 10, 2019

Scientists at the MDI Biological Laboratory Are Decoding the Genetic Mechanisms of Aging
Bioengineer.org · October 10, 2019

Scientists at the MDI Biological Laboratory Are Decoding the Genetic Mechanisms of Aging
BrightSurf.com · October 10, 2019

Scientists at the MDI Biological Laboratory Are Decoding the Genetic Mechanisms of Aging
Press Release · October 10, 2019

MDI Biological Laboratory Scientist Receives Federal Grant to Study Aging
Press Release · October 9, 2019

MDI Biological Laboratory Scientist Receives Federal Grant to Study Aging
Bio-IT World · October 9, 2019

MDI Biological Laboratory Scientist Receives Federal Grant to Study Aging
Bangor Daily News · October 9, 2019

100-plus Turn Out for Benefit Walk for Huntington’s Disease Research
Ellsworth American · October 29, 2018

Life Biosciences Funds MDI Biological Laboratory Aging Course
Bangor Daily News · August 16, 2018

MDI Biological Laboratory to Sponsor 'Live Longer, Live Better' Lecture Series
The Aging Insider (Gerontological Society of America) · August 10, 2018

MDI Biological Laboratory to Sponsor ‘Live Longer, Live Better’ Lecture Series
Bangor Daily News · August 6, 2018

MDI Biological Laboratory to Sponsor 'Live Longer, Live Better' Lecture Series
Life Extension Daily News · August 3, 2018

Anti-Aging Research Is Series Focus
Mount Desert Islander · August 3, 2018

MDI Biological Laboratory to Sponsor ‘Live Longer, Live Better’ Lecture Series
ALN Magazine · July 24, 2018

MDI Biological Laboratory To Sponsor ‘Live Longer, Live Better’ Lecture Series
BioIT World · July 24, 2018

MDI Biological Laboratory to Sponsor 'Live Longer, Live Better' Lecture Series
Press Release · July 23, 2018

IDeA Institutional Development Award Video: Mentoring the Future
National Institute of General Medical Sciences · July 7, 2018

Controlling Aging and Degenerative Disease
Voice of Maine radio · June 4, 2018

Voice of Maine "Senior Talk" Podcast on The Science of Longevity
Blueberry Broadcasting/Voice of Maine · March 7, 2018

The Connection Between Your Diet and Your Longevity
Breaking Through · December 7, 2017

The Connection Between Your Diet and Your Longevity
Catching Heath · December 6, 2017

Research Into Cellular Mechanism of Longevity Receives New Grant from National Institute on Aging
Regenerative Medicine Network · December 6, 2017

MDI Biological Laboratory Scientist Receives Grant to Study Aging
Bangor Daily News · November 30, 2017

MDI Biological Laboratory Scientist Receives Grant to Study Aging
BioIT World · November 30, 2017

MDI Biological Laboratory Scientist Receives Grant to Study Aging
Press Release · November 28, 2017

New Findings on Lifespan, Health
Mount Desert Islander · October 30, 2017

Walking in Support of Huntington’s Disease
Breaking Through · October 18, 2017

'Can We Slow the Aging Process?’ to Be Topic of MDI Science Café
Press Release · July 26, 2017

Living Long and Living Well: is it Possible to Do Both?
Regenerative Medicine Network · June 8, 2017

Living Long and Living Well: Is it Possible to do Both?
ALN Magazine · June 7, 2017

Living Long and Living Well: Is It Possible to Do Both?
Press Release · June 5, 2017

MDI Biological Laboratory's Maine Center for Biomedical Innovation Inspires Undergrads
Mount Desert Islander · April 3, 2017

Introduction to the MDI Biological Laboratory’s Center for Science Entrepreneurship
Regenerative Medicine Network · March 7, 2017

Prolonging Your Healthy Years: An Interview With Aric Rogers, Ph.D.
Breaking Through · March 3, 2017

Prolonging Your Healthy Years
Regenerative Medicine Network · March 3, 2017

Maine Scientist Makes Anti-Aging Discovery
WLBZ2 TV · March 2, 2017

Can a Really Strict Diet Prolong Your ‘Health Span’?
Bangor Daily News · February 27, 2017

MDI Biological Laboratory Breakthrough Roundworm Research
ABC7/Fox 22 · February 23, 2017

Research at MDI Biological Laboratory Sheds Light on Mechanisms Underlying Aging
Regenerative Medicine Network · February 16, 2017

Research at MDI Biological Laboratory Sheds Light on Mechanisms Underlying Aging
Bioengineer.org · February 16, 2017

MDI Biological Laboratory Research Uncovers Mystery of Why Diet Can Prolong Lifespan
Mainebiz · January 25, 2017

Research at MDI Biological Laboratory Sheds Light on Mechanisms Underlying Aging
Press Release · December 20, 2016

Eat Less, Live Longer
WABI TV5/The CW · November 3, 2016

MDI Bio Lab Inspires Art for a Visceral Experience of Science
Mainebiz · July 25, 2016

Live Long, Live Healthy, Live to 150? Scientists on MDI Say It Can Be Done.
Bangor Daily News · July 12, 2016

Living to Be 150
MPBN · June 30, 2016

MDI Biological Laboratory to Offer New Signature Course on Aging
Press Release · May 23, 2016

MDI Bio Lab Awarded $20K for Aging Research Program
Mainebiz · April 26, 2016

Scientists at the MDI Biological Laboratory Are Unlocking the Mechanisms of Parkinson’s Disease
Press Release · April 21, 2016

MDI Biological Laboratory Awarded Grant from Glenn Foundation to Study Aging
Press Release · April 20, 2016

MDI Researcher Looks to Roundworms to Unlock Secrets of Human Longevity
MPBN · March 25, 2016

International Team at the MDI Biological Lab Is Deciphering the Aging Code
Press Release · March 21, 2016

Going the Distance Against Parkinson's Disease
Press Release · October 27, 2015

MDI Biological Laboratory Scientist Receives Prestigious Award to Study Aging
Press Release · September 6, 2013

Assessing healthspan in C. elegans: Lessons from short-lived mutants. Rollins, J., Amber Howard, Sarah Dobbins, Elsie Washburn, and Aric N. Rogers (2017). The Journals of Gerontology: Series A, 72(4), 473–480. PMID: 28158466

Translational control of longevity in “Ageing: Lessons from C. elegans.” Rollins, J and Aric N. Rogers (2016). Chapter 13: eds. A Olson and MS Gill, Springer Publishing. doi:10.1007/978-3-319-44703-2_13

Comparative Biology of Tissue Repair, Regeneration, and Aging. Coffman, J. A., Sandra Rieger, Aric N. Rogers, Dustin L. Updike, and Viravuth P. Yin (2016). Nature Publishing Journals, Regenerative Medicine. doi:10.1038/npjregenmed.2016.3

Reducing translation through eIF4G/IFG-1 improves survival under ER stress that depends on heat shock factor HSF-1 in Caenorhabditis elegans. Howard AC, Rollins J, Snow S, Castor S, Rogers AN. Aging Cell. 2016 Aug 18

mTORC1/C2 and pan-HDAC inhibitors synergistically impair breast cancer growth by convergent AKT and polysome inhibiting mechanisms. Wilson-Edell KA, Yevtushenko MA, Rothschild DE, Rogers AN, Benz CC – Breast Cancer Res Treat. 2014 Feb 22.

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Dr. Rogers investigates the role of post-transcriptional mediators of gene expression on lifespan. Aging interventions of special focus include dietary restriction and genetic inhibition of translation initiation. The model organism employed in the lab is the small roundworm Caenorhabditis elegans. Undergraduate Research Fellows in the lab quickly learn basic handling and experimental procedures involving this nematode, which is especially useful for addressing basic questions of gene function via RNAi feeding.