MDI Biological Laboratory
Associate Professor

Aric Rogers, Ph.D.

How is gene expression remodeled under conditions that extend lifespan?

Using the model organism C. elegans, the Rogers Lab focuses at points of regulation that occur after transcription. Genetic variations and environmental conditions that result in lifespan extension are also associated with delaying the onset of age-related diseases including diabetes, cancer, and neurodegeneration. The goal of the Rogers Lab is to understand how life-extending interventions work across different species and apply what is learned to extend human health and longevity.

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Education

  • Ph.D., University of Massachusetts, Molecular and Cellular Biology, 2005

Student Projects

Dr. Rogers investigates the role of post-transcriptional mediators of gene expression on lifespan. Aging interventions of special focus include dietary restriction and genetic inhibition of translation initiation. The model organism employed in the lab is the small roundworm Caenorhabditis elegans. Undergraduate Research Fellows in the lab quickly learn basic handling and experimental procedures involving this nematode, which is especially useful for addressing basic questions of gene function via RNAi feeding.

Lab Members

Jordan HorrocksResearch Assistant II

Hussein SayedResearch Assistant II

Dilawar Mir, Ph.D.Postdoctoral Researcher

Zhengxin Ma, Ph.D.Postdoctoral Researcher