David Sinclair, Ph.D., a professor at Harvard Medical School and co-director of the Paul F. Glenn Center for the Biology of Aging, is known for his work on why we age and slowing aging’s effects. The goal of his laboratory is to establish new biological approaches that can be translated into radically different medicines to promote longer, more productive lives. He is especially interested in how genetic and epigenetic changes drive aging, common diseases and disorders such as cancer, heart disease, inflammation, neurodegeneration, infertility and diabetes. Another interest is sirtuins, a family of proteins that is a key regulator of longevity. Sinclair is the co-founder of several biotech companies. He is also co-founder and co-chief editor of the journal Aging. His work has been featured in books, documentaries and TV shows, including on “60 Minutes.” He is an inventor on more than 40 patents, has received more than 25 awards and was listed by TIME as one of the “100 most influential people in the world.”
The 36th Kinter Lecture is given in memory of William B. Kinter, Ph.D., an MDI Biological Laboratory investigator from 1963 until his death in 1978. His interest in the effect of toxic compounds on the environment led to landmark papers on the effect of pesticides on eggshell thinning in birds and important studies on the physiological effects of environmental pollutants, including crude oil.