MDI Biological Laboratory
Medical Course

Origins of Renal Physiology: Fellows 2024

A national course for renal fellows

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Application Deadline: 06/3/2024


Origins of Renal Physiology is entirely unique among national renal short courses. The course provides participants with research tools that give them a deeper understanding of concepts of physiological homeostasis which is difficult to attain during normal clinical training schedules.

In this course, trainees will perform experiments involving both classical physiological models, as well as modern reductionist approaches and confocal microscopy to follow trafficking of transporter proteins in cultured cells.

In addition to the curriculum itself, fellows will benefit from close interactions with senior investigators in renal physiology, who will guide them through the performance of the experiments, share meals with them in the dining room, and take the time to discuss their career goals with them. In addition, fellows will benefit enormously by working closely with other fellows from different programs, and sharing their insights into renal research.

The course is organized around several laboratory modules and one enrichment module in Responsible Conduct of Research.

  • Glomerular filtration rate
  • Proximal tubule function
  • Salt balance and secretion
  • Distal nephron sodium transport
  • Water homeostasis
  • Calcium oxalate stones

Participants will complete three of the rotations over the six-day course.  The first day of each rotation involves intensive experimental work, and the second day involves analysis and presentation of the work to the entire conference group.

Course Director

Mark Zeidel, M.D.

BIDMC, Harvard Medical School


Saturday    Sample Schedule subject to change.
4:00-6:00 pm Housing check-in
6:00 pm Welcome Dinner
7:00 pm Course Orientation
7:00-9:00 am Breakfast
8:30 am Rotation 1
12:00 pm Lunch
1:00 pm Rotation 1, continued
6:00 pm Dinner
7:30 pm Rotation 1, continued
7:00-9:00 am Breakfast
8:30 am Rotation 1, continued
10:00 am Large Lab Meeting
12:00 pm Lunch
1:00 pm Free Time for recreational activities
6:00 pm Dinner
7:00-9:00 am Breakfast
8:30 am Rotation 2
12:00 pm Lunch
1:00 pm Rotation 2, continued
6:00 pm Dinner
8:00 pm Rotation 2, continued
7:00-9:00 am Breakfast
8:30 am Rotation 2, continued
10:00 am Large Lab Meeting
12:00 pm Lunch
1:00 pm Free time for recreation
 6:00 pm Dinner
7:00-9:00 am Breakfast
8:30 am Rotation 3
12:00 pm Lunch
1:00 pm Rotation 3, continued
6:00 pm Dinner
7:00 pm Rotation 3, continued
7:00-9:00 am Breakfast
8:30 am Rotation 3, continued
10:00 am Large Lab meeting
12:00 pm Lunch
1:00 pm Free time for recreation
6:00 pm Lobster Bake
7:00-9:00 am Breakfast
by 9:00 am Self check-out from housing


Course participants reside in on-campus double occupancy housing. Single housing assignment, if available, may be arranged with an extra fee.


NIH funds can only be used to cover tuition for fellows and residents enrolled in US training programs. A non-refundable $500.00 registration fee is charged for all accepted participants to reserve their seat in the course.

US and International faculty members must pay tuition, and postdoctoral trainees in programs outside the US must pay tuition. Tuition for US faculty and International participants is $3,900.00 USD

Double-occupancy housing, meals, parking and wi-fi are provided to all accepted participants. Single occupancy, if available, may be purchased for an additional fee.


This course is supported by a research education grant from the National Institute of Diabetes and Digestive and Kidney Diseases (R25DK095727). US residents’ and fellows’ tuition is fully covered by grant funds.