In this course, trainees will perform experiments involving both classical physiological models such as toad urinary bladders, aglomerular toadfish, and zebrafish larvae, as well as modern reductionist approaches, such as two electrode voltage clamp studies of epithelial sodium channels expressed in Xenopus oocytes and confocal microscopy to follow trafficking of transporter proteins in cultured cells, and molecular biology.
In addition to the curriculum itself, fellows will benefit from close interactions with senior investigators in renal physiology, who will guide them through the performance of the experiments, share meals with them in the dining room, and take the time to discuss their career goals with them. In addition, fellows will benefit enormously by working closely with other fellows from different programs, and sharing their insights into renal research.
The course is organized around several laboratory modules and one enrichment module in Responsible Conduct of Research.
- Glomerular filtration rate
- Proximal tubule function
- Salt balance and secretion
- Distal nephron sodium transport
- Shark rectal gland
- Water homeostasis
- Acid-based homeostasis
Participants will complete three of the rotations over the six-day course. The first day of each rotation involves intensive experimental work, and the second day involves analysis and presentation of the work to the entire conference group.
Course Director
- Mark Zeidel, M.D.Herman Ludwig Blumgart Professor of MedicineBeth Israel Deaconess Medical Center
Rotation Leaders
- Dennis Brown, Ph.D.DirectorMGH Program in Membrane Biology, Harvard University
- Biff Forbush, Ph.D.Professor of Cellular And Molecular PhysiologyYale University
- John N. Forrest Jr., M.D.Professor of Medicine; Director of Student ResearchYale University School of Medicine
- Raymond A. Frizzell, Ph.D.Professor & Chairman, Department of Cell Biology and PhysiologyUniversity of Pittsburgh School of Medicine
- Hermann Haller, M.D.President, Professor, MDI Biological Laboratory; Professor, Director, Department of Nephrology and Hypertension, Hannover Medical SchoolMDI Biological Laboratory
- Orson Moe, M.D.ProfessorUT Southwestern
- Martin Pollak, M.D.Principal InvestigatorBeth Israel Deaconess Medical Center
- John Schwartz, M.D.ProfessorBoston University School of Medicine
Draft, subject to change
Saturday | |
4:00-6:00 pm | Housing check-inLate arrivals can pick up keys in the Dining Hall |
6:00 pm | Welcome Dinner, Dining Hall |
7:00 pm | Course Orientation, Maren Auditorium |
Sunday | |
anytime | Breakfast |
8:30 am | Rotation 1, Training Lab |
12:00 pm | Lunch |
1:00 pm | Rotation 1, continued |
6:30 pm | Dinner |
7:30 pm | Rotation 1, continued |
Monday | |
anytime | Breakfast |
8:30 am | Rotation 1, continued |
12:00 pm | Lunch |
12:30 pm | Large Lab Meeting, Maren Auditorium |
2:30 pm | Free Time for recreational activities |
7:00 pm | Dinner |
Tuesday | |
anytime | Breakfast |
8:30 am | Rotation 2 |
12:00 pm | Lunch |
1:00 pm | Rotation 2, continued |
6:30 pm | Dinner |
8:30 pm | Rotation 2, continued |
Wednesday | |
anytime | Breakfast |
8:30 am | Rotation 2, continued |
12:00 pm | Lunch |
12:30 pm | Large Lab Meeting, Maren Auditorium |
2:30 pm | Free time for recreation |
6:00 pm | Dinner |
Thursday | |
anytime | Breakfast |
8:30 am | Rotation 3 |
12:00 pm | Lunch |
1:00 pm | Rotation 3, continued |
6:30 pm | Dinner |
7:30 pm | Rotation 3, continued |
Friday | |
anytime | Breakfast |
8:30 am | Rotation 3, continued |
12:00 pm | Lunch |
12:30 pm | Large Lab meeting, Maren Auditorium |
2:30 pm | Free time for recreation |
6:00 pm | Dinner |
Saturday | |
anytime | Breakfast |
by 9:00 am | Self check-out from housing |
On-Campus Housing
Included. Housing is assigned. Please call 207-288-9880 ext 102 if you have any questions. Subject to availability.
Cottage-style accommodations are available with water front views. Our Cottages sleep 4-5 and are complete with full bathroom, kitchens, living room, high speed wireless internet, and parking.
Dormitory style cottage accommodations are available with double occupancy and single rooms, shared bathrooms, kitchenettes, common room, high speed wireless internet, and parking.
Our on-campus housing is within walking distance of all campus facilities (Note: campus grounds include wooded terrain).
Please visit our Housing Website to view our accommodations. Campus Map
This course is supported by a research education grant from the National Institute of Diabetes and Digestive and Kidney Diseases (1R25DK095727-01). US residents’ and fellows’ tuition is fully covered by grant funds.