Applications will open soon. To be notified, please contact the Education Office.
In this course, trainees will perform experiments involving both classical physiological models such as toad urinary bladders, aglomerular toadfish, and zebrafish larvae, as well as modern reductionist approaches, such as two electrode voltage clamp studies of epithelial sodium channels expressed in Xenopus oocytes and confocal microscopy to follow trafficking of transporter proteins in cultured cells, and molecular biology.
In addition to the curriculum itself, fellows will benefit from close interactions with senior investigators in renal physiology, who will guide them through the performance of the experiments, share meals with them in the dining room, and take the time to discuss their career goals with them. In addition, fellows will benefit enormously by working closely with other fellows from different programs, and sharing their insights into renal research.
The course is organized around several laboratory modules and one enrichment module in Responsible Conduct of Research.
- Glomerular filtration rate
- Proximal tubule function
- Salt balance and secretion
- Distal nephron sodium transport
- Water homeostasis
- Acid-based homeostasis
Participants will complete three of the rotations over the six-day course. The first day of each rotation involves intensive experimental work, and the second day involves analysis and presentation of the work to the entire conference group.
- Mark Zeidel, M.D.Herman Ludwig Blumgart Professor of MedicineBeth Israel Deaconess Medical Center
- Dennis Brown, Ph.D.DirectorMGH Program in Membrane Biology, Harvard University
- Biff Forbush, Ph.D.Professor of Cellular And Molecular PhysiologyYale University
- John N. Forrest Jr., M.D.Professor of Medicine; Director of Student ResearchYale University School of Medicine
- Hermann Haller, M.D.Professor; Director of the Department of Nephrology and HypertensionHannover Medical School
- Orson Moe, M.D.ProfessorUT Southwestern
- Martin Pollak, M.D.Principal InvestigatorBeth Israel Deaconess Medical Center
- Michael F. Romero, Ph.D.Professor of PhysiologyMayo Clinic
- John Schwartz, M.D.ProfessorBoston University School of Medicine
This course is supported by a research education grant from the National Institute of Diabetes and Digestive and Kidney Diseases (1R25DK095727-01). US residents’ and fellows’ tuition is fully covered by grant funds.