MDI Biological Laboratory

Gene Editing as a Tool to Study Neuronal Excitability: Bates College 2024

A short course for students from Bates College.


In this laboratory-based course, students investigate how lipids and proteins act together to regulate cellular activity. Using research facilities at Bates College and at Mount Desert Island Biological Laboratory near Bar Harbor, ME, students work with immortalized cell lines to address questions of neuronal signaling pathways by applying molecular, biochemical, and microscopy techniques. The course introduces students to the mathematical programming language R, and trains students in using R to analyze experimental data.

Learning goals include the following:
  • Characterize gene expression through quantitative RT-PCR
  • Analyze cellular signaling pathways using calcium imaging
  • Understand the basics of post-acquisition image processing and preparation of images for publication or presentation
  • Develop the skills required to analyze gene expression data using the programming language R

Bates logo


Martin Kruse

Bates College

About the Maine INBRE program

This short course is supported and organized by the Maine IDeA Network of Biomedical Research Excellence (INBRE).

Maine is one of 23 states that have been identified by the National Institutes of Health as having historically received low levels of NIH funding. The INBRE program was established to strengthen research networks in each of these states, so that they could become more competitive for federal research grants. In Maine, our network is comprised of 14 institutions, with the MDI Biological Laboratory as the lead institution. Other institutions in our network include the following: Bates College, Bowdoin College, Colby College, College of the Atlantic, the Honors College at the University of Maine, the Jackson Laboratory, Southern Maine Community College, the University of Maine, UMaine Farmington, UMaine Fort Kent, UMaine Machias, UMaine Presque Isle, and the University of New England.

Money from Maine INBRE supports research training experiences like this short course, as well biomedical research and laboratory facilities throughout our network. Other training experiences include academic year and summer student research. Please check with Ryan Bavis, the INBRE contact at Bates College, for the most accurate information about opportunities on your campus. He may be able to share additional opportunities with you as well.


This research training opportunity is supported by an Institutional Development Award (IDeA) from the National Institute of General Medical Sciences of the National Institutes of Health under grant number P20GM103423.

The IDeA program builds research capacities in states that historically have had low levels of NIH funding by supporting basic, clinical and translational research; faculty development; and infrastructure improvements.