Northeast Regional IDeA Conference 2015
Location: Bar Harbor Club, Bar Harbor, Maine (travel information)
The Sixth Northeast Regional Institutional Development Award (IDeA) Conference brings together individuals representing IDeA Networks of Biomedical Research Excellence (INBRE), Centers of Biomedical Research Excellence (COBRE), and IDeA Clinical and Translational Research programs from Delaware, Maine, New Hampshire, Rhode Island, and Vermont.
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Thank you for a wonderful conference.
Keynote Speaker: Marjana Tomic-Canic, Ph.D. Applied Basic Science: Understanding Biology and Pathology of Wound Healing
Professor of Dermatology and the Director of the Wound Healing and Regenerative Medicine Research Program at the Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine.
The conference will take place in Bar Harbor, Maine adjacent to Acadia National Park.
Fees
General Registration
$250.00
Student Discount Registration
$150.00
Partner
| Thursday, September 24, 2015 | |
| 1:45 – 9:30 pm | Registration Desk Hours of Operation |
| 2:00 – 5:00 pm | QBRI/Dartmouth COBRE Group Meeting |
| 2:00 – 6:00 pm | Registration and Poster Setup |
| 5:00 – 6:00 pm | Reception |
| 6:00 – 6:10 pm | Welcoming remarks from Patricia Hand, Ph.D., MDI Biological Laboratory and PI, Maine INBRE; and W. Fred Taylor, Ph.D., Acting Director, Center for Research Capacity Building, National Institute of General Medical Sciences (NIGMS) |
| 6:10 – 7:30 pm | Buffet Dinner |
| 7:30 – 9:00 pm | Northeast Regional IDeA States Showcase and Dessert Buffet Each IDeA Principal Investigator is invited to submit one poster that highlights one or more aspects of their program for this opening poster session and social gathering. |
| Friday, September 25, 2015 | |
| 7:00 – 5:30 pm | Registration Desk Hours of Operation |
| 7:00 – 8:30 am | Breakfast and Poster Set-up |
| 8:30 – 9:00 am | Opening Remarks from Jon Lorsch, Ph.D., Director, National Institute of General Medical Sciences (NIGMS) |
| 9:00 – 9:30 am | Overview of the IDeA Program, Yanping Liu, M.D., Ph.D., Program Director, Center for Research Capacity Building, National Institute of General Medical Sciences (NIGMS) |
| 9:30 – 9:50 am | Mid-morning Break and Refreshments |
9:50 am – 12:00 pm
Sponsored by
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Science Commercialization Workshop From Bench to Business: What you need to know to turn discovery into application |
| Scientists in academic settings may have projects with viable commercial potential, but often have no experience or ability to move the research into the market place. Commercialization of academic research is a difficult undertaking, but possible with the proper insight, knowledge, and resources. This workshop offers the opportunity to explore how one goes about moving research towards the market place. | |
| Chair: Kevin Strange, Ph.D., President, MDI Biological Laboratory, Chief Executive Officer, Novo Biosciences, Inc., PI, Maine COBRE | |
| 9:50 am | Finding ways to foster SBIR/STTR applications from IDeA states. Krishan Arora, Ph.D., NIH, National Institute of General Medical Sciences (NIGMS), Center for Research Capacity Building |
| 10:10 am | Investing in Innovation: The HHS SBIR/STTR Programs, Matt Portnoy, Ph.D., National Institute of Health, Division of Special Programs |
| Why do it? The trials, tribulations, and rewards of a biotech startup | |
| 10:45 am | From Bench to Product: Perspective is Everything, David Huizenga, Ph.D., J.D., TAO Life Sciences |
| 11:20 am | Launching a Company While Launching Your Career, Voot Yin, Ph.D., MDI Biological Laboratory, Chief Science Officer Novo Biosciences, Inc. |
| 11:40 am | Funding a Startup: From Business Plan to Payroll, Chuck Donnelly, RockStep Solutions, Inc. |
| 12:00 – 1:15 pm | Lunch and Discussion |
| 12:15 pm | NAIPI and Tracking IDeA Achievements Carolyn Bohach, Ph.D., University of Idaho and PI, Idaho INBRE, and President, National Association of IDeA Principal Investigators (NAIPI) Fred Taylor, Ph.D., Acting Director, Center for Research Capacity Building, National Institute of General Medical Sciences (NIGMS) |
| 12:45 pm | 2016 National IDeA Symposium of Biomedical Research Excellence Douglas Wright, Ph.D., Professor and Vice Chair, University of Kansas Medical Center, and PI, Kansas INBRE |
| 12:55 pm | Introduction to the Council on Undergraduate Research David S. Westerman, Ph.D., Division Chair, Council on Undergraduate Research (CUR), and Professor, Norwich University, VT. Dr. Westerman will be available to meet one-on-one with attendees throughout the meeting. |
| 1:15 – 3:30 pm | Concurrent Scientific Sessions |
| 1:15 – 3:30 pm | Session 1: Tissue Repair, Regeneration, and Developmental Biology Chair: Peter Quesenberry, M.D., Brown University Barbara B. Knowles, Ph.D., The Jackson Laboratory |
| 1.1 Sandra Rieger: IKKα serves as an innate surveillant for hydrogen peroxide-dependent wound re-epithelialization
1.2 Eric Kmiec: Regulation of gene editing for chromosomal translocation and gene repair in mammalian cells 1.3 Calvin Vary: Lipidomic comparison of mouse adipose tissue compared to cell models of adipocyte differentiation 1.4 Voot Yin: Dynamic MicroRNA-101a/Fosab Expression Controls Zebrafish Heart Regeneration 1.5 Don Wojchowski: EPO modulation of Thioredoxin Interacting Protein (TXNIP), and key roles for TXNIP during EPO-dependent human erythroid progenitor development 1.6 Lei Lei: From Development to Disease: function of transcription factor Sox11 in neurogenesis, nerve regeneration, and chronic pain 1.7 Benjamin King: The Comparative Models of Regeneration Database (RegenDB) |
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| 1:15 – 3:30 pm | Session 2: Cancer Biology, Immunology and Infectious Disease Chairs: William Green, Ph.D., Geisel School of Medicine at Dartmouth and Bharat Ramratnam, M.D., Brown University |
| 2.1 Melissa Maginnis: Defining the host-pathogen interactions of JC polyomavirus infection
2.2 Amy Schaefer: Recovery and Response of Crohn’s Associated Mutants to Bacterial Cell Wall Fragments 2.3 Robert Wheeler: Dynamics of Candida-host interaction in vivo 2.4 Shuhua Bai: Exosome delivery of small interfering RNA for Brain Cancer Therapy 2.5 Eyal Amiel: Dectin-1-mediated Metabolic Reprogramming Mediates Inflammasome Activation 2.6 Constance Brinckerhoff: A novel murine model of BRafV600E mutant melanoma |
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| 1:15 – 3:30 pm | Session 3: Epidemiology and Toxicology Chairs: Margaret R. Karagas, Ph.D., Geisel School of Medicine at Dartmouth and Zahir Shaikh, Ph.D., University of Rhode Island College of Pharmacy |
| 3.1 Md Jobayer Hossain: Characterization of the Aplastic Anemia (AA) and Its Survival Outlook in the Pediatric Population
3.2 Larissa Williams: Response to structurally diverse pro-oxidant exposure during development 3.3 Joyce Thompson: Asbestos-Induced Mesothelial to Fibroblastic Transformation: An Escape to Pathogenesis? 3.4 Nathan Martin: Differences in ROS production in BEAS-2B cells exposed to ‘real world’ diesel and biodiesel particulate matter 3.5 Adam Black: Human and mouse studies of endoglin in Diabetes and Diabetic Nephropathy 3.6 Tracy Punshon: Imaging the placental metallome in the New Hampshire Birth Cohort |
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| 1:15 – 3:30 pm | INBRE Evaluators Meeting Facilitated by Sharon O’Connor, M.B.A., M.S., Center for Program Design and Evaluation at Dartmouth |
| 1:15 – 3:30 pm | IDeA Shared Instrumentation and Technology Centers Meeting Facilitated by Katia Sol-Church, Ph.D., Director, DE-INBRE Centralized Research Instrumentation Core |
| 1:15-1:20 pm | Introducing the North East Regional Memorandum of Understanding. Katia Sol-Church, Ph.D. |
| 1:20-2:20 pm | Shared Resource Sections of COBRE, INBRE, and SIG Grants: What reviewers are looking for. Steven Fiering, Ph.D., Yanping Liu, M.D., Ph.D., Rob Akin, Ph.D., F.A.H.A. |
| 2:25-3:30 pm | NCIL Open Forum: Sharing of Core Resources across the North East IDeA States: Turning those nickels into gold. Alvin Bach, Ph.D., Steven Fiering, Ph.D., Tim Hunter Sandra Rieger Ph.D., Katia Sol-Church, Ph.D. |
| 1:15 – 3:30 pm | Informal Networking and Discussion Session |
| Moderators: Scott Somers, Ph.D., Division of Pharmacology, Physiology, and Biological Chemistry, Division of Training, Workforce Development and Diversity, Division of Biomedical Technology, Bioinformatics, and Computational Biology, Coordinator, SBIR/STTR Program, NIGMS |
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| Krishan Arora, Ph.D., Center for Research Capacity Building, National Institute of General Medical Sciences (NIGMS) | |
| 1:15 – 2:15 pm | Alternative Careers Undergraduate students, graduate students and postdoctoral fellows often may not have a clear understanding of what career options exist, partly because many academic institutions and mentors themselves do not have a broad perspective. The round table offers students and postdoctoral fellows the opportunity to have either small group or one-on-one discussions with NIGMS staff and peers to ask questions, get general advice, and learn about career paths in academia and beyond. |
| 2:15 – 3:15 pm | Assisting the Academic Innovators Scientists in academic settings may have projects with viable commercial potential, but often have no experience or ability to move the research into the market place. Commercialization of academic research is a difficult undertaking, but possible with the proper insight, knowledge, and resources. The roundtable offers the chance to meet with NIGMS staff to explore how one goes about moving research towards the market place. |
| 3:30 – 3:45 pm | Break |
| 3:45 – 4:45 pm | Keynote Lecture: Marjana Tomic-Canic, Ph.D., University of Miami Miller School of Medicine. Applied Basic Science: Understanding Biology and Pathology of Wound Healing. Introduction by Sandra Rieger, Ph.D., MDI Biological Laboratory. |
| 4:45 – 6:00 pm | Poster Session A |
| 6:00 pm | Dinner on your own |
| 6:00 – 9:30 pm | Meeting of IDeA PIs and NIH officials at MDI Biological Laboratory |
| Saturday, September 26, 2015 | |
| 7:00 – 2:00 pm | Registration Desk Hours of Operation |
7:30 – 9:00 am
Sponsored by
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Science Commercialization Panel Breakfast Moderator: David Huizenga, Ph.D., J.D., Co-founder and Chief Executive Officer, Tao Life Sciences |
| Kevin Strange, Ph.D., President, MDI Biological Laboratory, Chief Executive Officer, Novo Biosciences, Inc., PI, Maine COBRE | |
| Voot Yin, Ph.D., Assistant Professor, Kathryn W. Davis Center for Regenerative Biology and Medicine, MDI Biological Laboratory, Chief Science Officer, Novo Biosciences, Inc. | |
| Matthew Portnoy, Ph.D., Division of Special Programs, Office of Extramural Programs, and SBIR/STTR Program Coordinator, National Institutes of Health (NIH) | |
| Joe Migliaccio, Director of Business Development, Maine Technology Institute | |
| Chuck Donnelly, Chief Executive Officer, RockStep Solutions, Inc. | |
| Mercedes Rincon, Ph.D., Professor of Medicine, Immunobiology Medicine, Department of Medicine, University of Vermont, Vermont SPARK program | |
| 8:00 – 9:00 am | Science Careers Breakfast Discussion |
| Undergraduate students, graduate students and postdoctoral fellows often may not have a clear understanding of what career options exist, partly because many academic institutions and mentors themselves do not have a broad perspective. The round table offers students and postdoctoral fellows the opportunity to have either small group or one-on-one discussions with NIGMS staff and peers to ask questions, get general advice, and learn about career paths in academia and beyond. | |
| Scott Somers, Ph.D., Division of Pharmacology, Physiology, and Biological Chemistry, Division of Training, Workforce Development and Diversity, Division of Biomedical Technology, Bioinformatics, and Computational Biology, Coordinator, SBIR/STTR Program, NIGMS | |
| Krishan Arora, Ph.D., Center for Research Capacity Building, National Institute of General Medical Sciences (NIGMS) | |
| Yanping Liu, M.D., Ph.D., Program Director, Center for Research Capacity Building, National Institute of General Medical Sciences (NIGMS) | |
| 9:00 – 10:00 am | Poster Session B |
| 10:00 – 12:00 pm | Concurrent Scientific Sessions |
| 10:00 – 12:00 pm | Session 4: Bioinformatics and Computational Biology Chairs: James Vincent, Ph.D., University of Vermont and Benjamin King, M.S., MDI Biological Laboratory |
| 4.1 Erin Crowgey: Bioinformatics in Precision Medicine: Pediatric Clinical Genomic NGS (Next Generation Sequencing) Data Analysis
4.2 Edward Lyman: Unraveling the role of lipids as mediators of GPCR function 4.3 Clare Congdon: Computational inference of regulatory regions for mesangial-expressed genes 4.4 Jason Castro: Genome-scale analysis of olfactory system heterogeneity 4.5 Benjamin King: A Conserved Gene Regulatory Circuit during Appendage Regeneration in Three Vertebrates 4.6 Jennifer Wyffels: Integrated wet and dry lab education using the Skate Genome Project |
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| 10:00 – 12:00 pm | Session 5: Pulmonary and Cardiovascular Systems Chairs: Bob Friesel, Ph.D., Maine Medical Center Research Institute and Charles Irvin, Ph.D., University of Vermont |
| 5.1 Rhonda Prisby: Ossified bone marrow blood vessels, bone volume and hematological parameters in Fischer-344 rats and humans
5.2 Carolyn MacDonald: Combined effects of intermittent hyperoxia and intermittent hypercapnic hypoxia on development of the control of breathing in rats 5.3 Iwona Buskiewicz: Novel interaction of toll like receptor 4 and decay accelerating factor promotes autophagy induction during CVB3 infection 5.4 Samantha Meenach: Aerosol Particulates Capable of Penetrating Pulmonary Physiological Barriers |
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| 10:00 – 12:00 pm | Session 6: Neuroscience and Behavior Chairs: Judith Van Houten, Ph.D., University of Vermont and Melissa Harrington, Ph.D., Delaware State University |
| 6.1 Casey Acklin: Genetic profiling of early Alzheimer’s disease: a focus on the JAK/STAT pathway
6.2 Ling Cao: Role of CD4 in spinal cord chemokine responses in a murine model of neuropathic pain 6.3 Hadley Horch: Compensatory Recovery in the CNS after Auditory System Damage 6.4 Michael Gitcho: The role of TDP-43 in Alzheimer’s Disease 6.5 Kayla Gjelsvik: Bone Morphogenetic Proteins (BMPs) are Necessary for Pain Sensitization in Drosophila melanogaster 6.6 Dana Thompson: The impact adverse childhood experiences have on flourishing among children |
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| 12:00 – 1:00 pm | Lunch and Professional Networking An opportunity for informal discussions. Boxed lunches will be provided. |
| 1:00 pm | Conference concludes |
| 2:00 pm | Registration Desk Closes |
Discounted Hotel Room Blocks
- Bar Harbor Regency: 123 Eden Street, Bar Harbor, ME 04609. 1-800-234-6835
This hotel is 1.4 miles from the conference venue. Shuttle service is available.
Group Code: MDI- $175.00/night (Eden House 2 double beds)
- $193.00/night (Parkview 2 double beds)
Rooms still available at our discounted room block rate.
- Harborside Hotel Marina & Spa: 55 West Street, Bar Harbor, ME 04609. 1-800-328-5033
This hotel is adjacent to the conference venue and a short walk to downtown Bar Harbor.
Group Code: MDIAUG2014
Book Online Direct with conference rate- $238.00/night (Deluxe 2 Doubles, Standard View)
- $264.00/night (Premium 1 King, Island View)
Room block is sold out. Call for availability.