MDI Biological Laboratory

Archive for: Regeneration

Comparative Biology: Animal Models Strut Their Stuff

  At MDIBL, researchers are particularly focused on the mechanisms of aging and regeneration. Non-mammalian model organisms like C. elegans, zebrafish, African turquoise killifish, and the axolotl regenerate naturally in ways that humans cannot. By decoding the instruction manual for their regenerative abilities, we can develop new strategies to enhance our natural ability to repair…

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Who Is Coming to the Regeneration Party?

MDI Biological Laboratory scientist, James Godwin, Ph.D., who studies heart and limb regeneration in the axolotl, a highly regenerative Mexican salamander, likes to compare the process of regeneration that takes place at the site of an injury to a party. Over the course of his career, he has identified who comes to the regeneration party…

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Meet Our Postdocs: Marko Pende, Ph.D.

When Prayag Murawala, Ph.D., was recruited as a new faculty member to MDI Biological Laboratory in 2020, it only took a few months for colleague Marko Pende, Ph.D., to follow him to Maine as a postdoctoral researcher. Marko and Prayag collaborated on a paper while they were both completing different stages of their education and…

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Making a Mouse More Like an Axolotl: How James Godwin’s Discoveries Are Helping Science ‘Pull the Levers of Regeneration’

Science is now inching closer to the answer thanks to new research by MDI Biological Laboratory scientist James Godwin, Ph.D. Following in the laboratory’s tradition of using comparative biology to gain insights into human health, Godwin has compared the molecular mechanisms governing regeneration in a highly regenerative salamander to those in the mouse, which has…

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Research by Iain Drummond, Ph.D., Brings Science Closer to Kidney Replacement Tissue

Each of the body’s approximately one million nephrons, the functional units of the kidney, contains a glomerulus, or a cluster of blood vessels where filtration takes place. The membranes of the glomeruli are lined with specialized cells called podocytes, which have tiny, foot-like projections (podo means “having a foot” in Latin) that protrude into the…

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Limb Regeneration: Fitting the Pieces of the Puzzle Together

“I think of the former state of the field as a puzzle in which the pieces have no pictures. Now, with the molecular and genetic tools in place, it can be thought of as a puzzle with pictures on the pieces, which means that the real work of fitting the pieces together can begin.” Prayag…

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MDI Biological Laboratory welcomes Prayag Murawala, Ph.D.

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This is Why: Elisabeth Marnik, Ph.D., Postdoctoral Researcher

“The research and education we do here is so important for future generations, and I’m glad I can be part of it.” Elisabeth Marnik, Ph.D., Postdoctoral Researcher Elisabeth says that being at the MDI Biological Laboratory has given her the opportunity to not only conduct and publish really exciting research, but she’s had the chance…

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MDIBL celebrates promotion of Dustin Updike, Ph.D., to Associate Professor

“You can’t overstate the effect that walking to work through this beautiful campus has on your well-being.  It clears your head and prepares you to do the best science possible.” Dustin Updike, Ph.D. The MDIBL community recently came together to celebrate the promotion of Dustin Updike, Ph.D., to Associate Professor. In the seven years that…

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