MDI Biological Laboratory

Topic: Aging

Sonia Sandhi’s Journey to a Ph.D. in Aging Research

Sonia Sandhi grew up not knowing what a Ph.D. was — she knows now. Sonia just earned her doctorate in the latest sign of momentum for MDI Bio Lab’s graduate fellowship program.

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A New Transgenic Fish Speeds Research on Age-Related Muscle Decline

Pioneering research published in PLOS Genetics establishes a new way to accelerate the study of sarcopenia and potential therapies in a live vertebrate. 

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A Fast-Aging Fish Reveals How a Familiar Drug Preserves Youthful Kidney Function

MDI Bio Lab scientists pioneer the use of African turquoise killifish as a powerful model for human aging, and reveal the specific biological mechanisms at work when a class of drugs called SGLT2 inhibitors help to preserve tissue health. The discoveries open a door for new research under the Lab’s MDI Bioscience initiative on whether the drugs can not only help maintain healthy organs as we age, but reverse damage and increase longevity. 

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Leaders in Regenerative & Developmental Biology Converge on MDI Bio Lab campus

Second annual ReBilD course marks Lab’s leadership in the field

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How to Keep Blood Vessels Young and Fight Aging

Anastasia Paulmann, M.D., works with a unique, short-lived fish to study how the vascular system changes with age and test a new therapy to prevent those changes.

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Unlocking the Secrets of Vision Restoration

Exploring the zebrafish’s self-healing powers. Can we apply them to humans?

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African Turquoise Killifish in Focus at National Conference Hosted by MDI Bio Lab

Anastasia Paulmann, M.D., a postdoctoral researcher in the laboratory of Hermann Haller, M.D., has adopted the remarkable African turquoise killifish as a model for aging studies. It’s a rising star in comparative biology, and Paulmann co-organized the first national conference dedicated to its development.

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Rising Investigator Appointed to MDI Bio Lab Faculty

Emily Spaulding explores how disrupting basic cell organization leads to neurodegenerative disease

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New Findings Shed Light on Mitochondrial Function

Research on mitochondrial function in Drosophila published in the journal Life Science Alliance.

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