General News
2022 MDI Biological Laboratory Publications
- January 1, 2023
In 2022 MDI Biological Laboratory’s researchers continued to push into new scientific frontiers in the biology of aging, repair and regeneration, expanding our knowledge of how to protect and extend healthy lifespans.
Faculty Publications
Frontiers in Cell and Developmental Biology, Editorial: Early life stress and developmental programming of immune and nervous system responsivity
- eLife, Single-cell transcriptome reveals insights into the development and function of the zebrafish ovary
- Journal of the American Society of Nephrology, Slit diaphragms: Junctions that never sleep
- Science Advances, Top2a promotes the development of social behavior via PRC2 and H3K27me3
- Disease Models and Mechanisms, Variable phenotypes and penetrance between and within different zebrafish ciliary transition zone mutants
Methods in Molecular Biology, Cell dissociation techniques in salamanders
- Herz, Cardiorenal benefits of mineralocorticoid antagonists in CKD and type 2 diabetes: Lessons from the FIGARO-DKD trial
- Scientific Reports, Calcium dobesilate reduces SARS-CoV-2 entry into endothelial cells by inhibiting virus binding to heparan sulfate
- Nature Methods, A hybrid open-top light-sheet microscope for versatile multi-scale imaging of cleared tissues
- Development, Growth, and Differentiation, Inducible and tissue-specific cell labeling in Cre-ER(T2) transgenic Xenopus lines
- Methods in Molecular Biology, FlyClear: A tissue-clearing technique for high-resolution microscopy of Drosophila
- Methods in Molecular Biology, Baculovirus production and infection in axolotls
- Frontiers in Genetics, Muscles are barely required for the patterning and cell dynamics in axolotl limb regeneration
Science Advances, Exportin 1 modulates life span by regulating nucleolar dynamics via the autophagy protein LGG-1/GABARAP
- PLoS Genetics, The Caenorhabditis elegans TDRD5/7-like protein, LOTR-1, interacts with the helicase ZNFX-1 to balance epigenetic signals in the germline
- Developmental Biology, GLH-1/Vasa represses neuropeptide expression and drives spermiogenesis in the C. elegans germline*
- Nature Communications, RG/RGG repeats in the C. elegans homologs of Nucleolin and GAR1 contribute to sub-nucleolar phase separation
*Collaboration is a hallmark of MDI Biological Laboratory and these publications were joint works between MDIBL research labs.
Visiting Scientists or Former Faculty:
Fricker Lab:
Aquatic Toxicology, Sodium arsenite but not aluminum chloride stimulates ABC transporter activity in renal proximal tubules of killifish (Fundulus heteroclitus)
Rieger Lab: