General News

2022 MDI Biological Laboratory Publications

January 1, 2023

In 2022 MDI Biological Laboratory’s researchers continued to push into new scientific frontiers in the biology of aging, repair and regeneration, expanding our knowledge of how to protect and extend healthy lifespans.

Faculty Publications

Coffman Lab:

Frontiers in Cell and Developmental Biology, Editorial: Early life stress and developmental programming of immune and nervous system responsivity

Drummond Lab:

eLife, Single-cell transcriptome reveals insights into the development and function of the zebrafish ovary
Journal of the American Society of Nephrology, Slit diaphragms: Junctions that never sleep
Science Advances, Top2a promotes the development of social behavior via PRC2 and H3K27me3
Disease Models and Mechanisms, Variable phenotypes and penetrance between and within different zebrafish ciliary transition zone mutants

Godwin Lab:

Methods in Molecular Biology, Cell dissociation techniques in salamanders

Haller Lab:

Murawala Lab:

Nature Methods, A hybrid open-top light-sheet microscope for versatile multi-scale imaging of cleared tissues
Development, Growth, and Differentiation, Inducible and tissue-specific cell labeling in Cre-ER(T2) transgenic Xenopus lines
Methods in Molecular Biology, FlyClear: A tissue-clearing technique for high-resolution microscopy of Drosophila
Methods in Molecular Biology, Baculovirus production and infection in axolotls
Frontiers in Genetics, Muscles are barely required for the patterning and cell dynamics in axolotl limb regeneration

Rogers Lab:

Science Advances, Exportin 1 modulates life span by regulating nucleolar dynamics via the autophagy protein LGG-1/GABARAP

Updike Lab:

PLoS Genetics, The Caenorhabditis elegans TDRD5/7-like protein, LOTR-1, interacts with the helicase ZNFX-1 to balance epigenetic signals in the germline
Developmental Biology, GLH-1/Vasa represses neuropeptide expression and drives spermiogenesis in the C. elegans germline*
Nature Communications, RG/RGG repeats in the C. elegans homologs of Nucleolin and GAR1 contribute to sub-nucleolar phase separation

*Collaboration is a hallmark of MDI Biological Laboratory and these publications were joint works between MDIBL research labs.

Visiting Scientists or Former Faculty:

Fricker Lab:

Aquatic Toxicology, Sodium arsenite but not aluminum chloride stimulates ABC transporter activity in renal proximal tubules of killifish (Fundulus heteroclitus)

Rieger Lab:

PNAS, Coordinated NADPH oxidase/hydrogen peroxide functions regulate cutaneous sensory axon de- and regeneration

MDIBL’s Work in 2022 Includes a New Way To Prevent COVID-19 Infection

Over the course of the year just past, MDI Biological Laboratory’s researchers continued to push the frontiers in the biology of aging, repair, and regeneration, expanding our knowledge of how to protect and extend healthy lifespans.

UNE, MDIBL Team up for Drinking Water Initiative

Collaboration with “Legacy Scholars” builds on the Laboratory’s “All About Arsenic” citizen science initiative